These key enzymes can control the occurrence of type II diabetes (α-amylase and α-glucosidase), obesity (lipase) and AD (acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and β-secretase (BACE-1)) (Table 3). This evidence concerns the gene BCHE and obesity due to melanocortin 4 receptor deficiency.