The CAC-associated pro-inflammatory cytokines, TNF-α (Figure 1A) and IL-6 (Figure 1B) and CCM from PANC-1 human pancreatic cancer cells (Figure 1C) promoted lipolysis in mature 3T3-L1 adipocytes as judged by an increase in glycerol release and free fatty acids (FFA). Here, IL6 is linked to familial pancreatic carcinoma.