NPPB and heart failure: The latest NICE guidelines [87] also recommend dosing NT-proBNP in people with suspected heart failure, but they also recommend undergoing a specialist evaluation with the execution of a transthoracic echocardiogram within 2 weeks for patients with NT-proBNP values > 2000 ng/L and within 6 weeks for patients with values between 400 and 2000 ng/L.