BRCA1 and endometrial cancer: In contrast, Kitson et al. found no significant increased risk for endometrial cancer in the 2609 included in their study for both BRCA1/2m [SIR = 1.70 (95% CI, 0.74–3.33)] [37] as well as Goshen et al., even if they did not consider 2 of the 3 BRCA1 mutations examined in many other studies [20].