The clinicopathological analyses were performed for FGFR1, FGFR2, FGFR3 and FGFR4 against age, sex, grade stages, tumor stages, HCV, AFP, cirrhosis, vascular invasion, and cell type (atypical, dysplastic/polygonal, neoplastic) using different statistical approaches. This evidence concerns the gene FGFR1 and Cirrhosis.