These results have a counterpart in the literature, where immunophenotyping of SCD patients off therapy was characterized by neutrophilic, lymphocytic and monocytic leukocytosis, along with a prevalence of memory on naïve T cells, interesting in a particular CD8+ subset in a context of T-cell compartment enlargement [5,15,16,17,18,19,20,21]. Here, CD8A is linked to Schnyder corneal dystrophy.