Patients with LN showed significantly higher serum levels of DKK3 when compared to those without renal involvement (median [min-max] DKK3 levels were 215 ng/mL [81–341] vs. 21.1 ng/mL [1–69] ng/mL, p < 0.01, respectively) (Figure 1). The gene discussed is DKK3; the disease is lobular neoplasia.