Among additional MS-repurposable drugs prioritized by SAveRUNNER and classified as histaminergic drugs, of particular note is rupatadine (DrugBank accession number DB11614; brand name Rupall; a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis and chronic spontaneous urticaria), with network-based similarity value = 0.6279, and p-value = 0.0141, ranking in position 243 of the list. This evidence concerns the gene PTAFR and chronic idiopathic urticaria.