EWSR1 and histiocytoma, Angiomatoid fibrous: For example, EWSR1-ATF1 or EWSR1-CREB1 chromosomal translocations can give rise to both clear cell sarcoma and angiomatoid fibrous histiocytoma, which are two STS subtypes with distinct morphological and clinical features (Figure 1A) [39,85,86].