MGMT and neoplasm: In a study [26] that focused on developing a new technology—a sensitive microfluidic platform for on-chip analysis of mRNA contents of exosomes—it was found that DNA methyltransferase MGMT (O-6-methylguanine DNA methyltransferase) mRNA is not only detectable in exosomes, but the levels are reflective of changes in the parental tumor cells.