A transcriptomic analysis of TAMs isolated from the ascites of OC patients revealed two signatures of expressing genes: A, characterized by the overexpression of pro-tumor and immunosuppressive markers (CD163, PCOLCE2, IL6) related to ECM remodeling; and B, with low expression of pro-oncogenic and immunosuppressive markers and increased regulation of genes associated with interferon signaling [96]. This evidence concerns the gene IL6 and neoplasm.