They involve STAT3-inducing cytokines (IL-10, IL-6 and LIF), TGFB1 mainly expressed by TAMs, WNT7A mainly expressed by tumor cells, multiple S100 genes, semaphorins and their receptors (plexins and neuropilins), ephrins, chemokines and their receptors [91]. This evidence concerns the gene STAT3 and neoplasm.