Among the five S-deficiency-responsive genes in the shoots, the expressions of three genes were recovered after homogenous or heterogeneous sulfate resupply, including the APR (Os07g0509800), SAT (Os03g0185000), and OAS-TL (Os06g0564700) (Figure 5C; Table S7). The gene discussed is SMOC1; the disease is hyperinsulinemic hypoglycemia, familial, 4.