INS and Huntington disease: The DEGs in LM + BL vs. CON were enriched in the functions of neurons (neuron part, neuron projection, neuronal cell body), cells (cell body, cell projection, respirasome, plasma-membrane-bounded cell projection), and synapses (calcium-ion-regulated exocytosis of neurotransmitters, synaptic vesicle exocytosis, signal release), and were mainly involved in pathways of some disease (Parkinson’s disease, oxidative phosphorylation, Huntington’s disease, thermogenesis, retrograde endocannabinoid signaling), mucin and other types of O-glycan biosynthesis, and insulin secretion (Figure 3B,C).