The predictive accuracy of IL-9, IL-17, PDGF-bb and RANTES could not be validated in a larger cohort from the DILIN and Acute Liver Failure Study cohort, in this cohort the only predictive panel was RANTES and albumin, which at lower levels predicted mortality within six months with a specificity of 91% at a low sensitivity of 39%. This evidence concerns the gene IL9 and acute liver failure.