Neither of the two dosages tested induced significant improvements in the end-point parameters measured, including urinary albumin, albumin–creatinine or protein–creatinine ratio, creatinine clearance, lipid profile, and glycated hemoglobin (HbA1c) level at week 12 [86], demonstrating a lack of efficacy of naïve BM-MSCs in the management of diabetic nephropathy. This evidence concerns the gene ALB and diabetic kidney disease.