HMGCS2 and rectal cancer: The overexpression of two lipid biosynthesis-associated genes, 17β-hydroxysteroid dehydrogenase type 2 (17HSD2) and mitochondrial enzyme 3-hydroxy-3-methylglutaryl-CoA synthase (HMGCS2), was associated with poor response to concurrent chemoradiotherapy treatment in the biopsies of 46 rectal cancer patients.