AKT1S1 and neoplasm: To obtain further insight into the molecular mechanisms downstream of PLOD2 in GBM cells, we assessed by western blot the protein expression of several markers associated with tumor proliferation and invasion, such as Catenin D1, CD44, CD99, CDK6, EGFR, HIF1-beta, Integrin beta-1, MT1-MMP and PRAS40.