PLOD2 and glioblastoma: In both cohorts, high expression of PLOD2 predicted poor OS in GBM patients (Hannover cohort: HR = 1.401, CI [95%] = 1.009–1.946, p = 0.044; Magdeburg cohort: HR = 1.493, CI [95%] = 1.042–2.140, p = 0.029) (Figure 2A).