TACR1 and Bartsocas-Papas syndrome 1: Moreover, miR-499b-5p, miR-500a-5p, miR-328-3p and miR-320a-3p were upregulated in biopsies of BPS patients and negatively correlated with NK1R mRNA and/or protein levels, indicating that BPS can lead to an attenuation of NK1 tachykinin receptor synthesis via activation of these miRNAs [72].