Risk factors for cutaneous melanoma also include freckles, intense sun exposure and strong skin reactions to sun as well as genetic mutations in a panel of genes such as CDKN2A, MC1R (melanocortin 1 receptor), MITF (microphthalmia-associated transcription factor) and BAP1 (BRCA1 associated protein 1) [13]. The gene discussed is MC1R; the disease is cutaneous melanoma.