NFKB1 and COVID-19: Regarding the underlying signaling pathways, several reports indicate the NF-κB pathway as one of the critical signaling pathway for the SARS-CoV-2 infection-induced proinflammatory cytokine/chemokine response, playing a central role in the severity and lethality of COVID-19, probably in the context of related pathways such as the IL-6/STAT pathway [40,41,42,43,44,45,46].