SOD1 and malaria: Moreover, Tyagi et al. [132] found a decrease in the activity of SOD, CAT, and GST, simultaneously with the increase in GSH and MDA in patients with untreated malaria and, when starting treatment with antimalarials, the inversion of this condition was observed i.e., the increased SOD, CAT, and GST activities, followed by the reduction of GSH and MDA.