The expression pattern and quantitative analysis of connexins 37, 40, 43 and 45 and pannexin 1 markers was performed on tissue sections of 8th, 10th and 12th week of development of the human eye, and in retinoblastoma, normal postnatal human eye and uveal eye melanoma, using hematoxylin and eosin (Figure 1) and immunofluorescence staining (Figure 2, Figure 3, Figure 4, Figure 5 and Figure 6). The gene discussed is PANX1; the disease is retinoblastoma.