Not only typical fibrotic disorders, but also several diseases accompanied by fibrotic changes in tissues, such as atherosclerosis [118], proliferative retinopathy [119] and neuromuscular diseases, such as several types of muscular dystrophy, muscle denervation, amyotrophic lateral sclerosis and spinal muscular atrophy [117] are known to be related to CCN2. The gene discussed is CCN2; the disease is muscular dystrophy.