PRL and esophageal squamous cell carcinoma: To date, a number of studies concerning the role of miR-375 have been reported to be influenced in normal pancreatic genesis [28], the proinflammatory macrophage response [29], pituitary prolactin synthesis [30], neuroendocrine differentiation and tumorigenesis in lung carcinoid cells [31], inhibition in proliferation and invasion of nasopharyngeal carcinomas [32], and inhibition in the proliferation, migration, and invasion of esophageal squamous cell carcinomas [33].