LYST and Pallister-Hall syndrome: Venn diagrams showed that adenosine, cAMP, and oxaloacetic acid were specific to CHS; however, L-arginine, L-asparagine, L-carnitine, L-homocysteine, L-methionine, myo-inositol, nicotinic acid, and pyridoxine were specific to the PHS group (Figure 5c).