The miR-378 sequence is located at the 5′ end of the PGC-1β mRNA sequence; therefore, this small molecule further silences its targeting genes, such as KLK2, KLK4, KLK6, KLK14, etc. All the results showed that this significantly induced cell apoptosis in the PCa cells, which was proven in cell viability, cell death, and apoptosis assay experiments (p < 0.05) (Figure 6). Here, KLK14 is linked to posterior cortical atrophy.