KLK3 and posterior cortical atrophy: Herein, we hypothesized that miR-378 may play a crucial role in silencing the pivotal PCa-related genes, such as the KLK gene family, in which KLK3 is a gene encoding the glycoprotein enzyme in humans, which is a well-known prostate-specific antigen (PSA), and acts as the contemporary serum biomarker for PCa diagnosis.