The BeSS-based model selected a panel of six genes with the exclusion of BIRC5 and PINK1 (Figure S5A); their elimination is largely attributable to their high levels of correlation with other genes (Figure S5B), i.e., their presence does not add to the biomarker potential of the resultant multigene panel (SigCmbn_B) in predicting ACC relapse and prognosis. The gene discussed is BIRC5; the disease is adrenal cortex carcinoma.