The invasion in the close proximity of the tumor (liver, visceral, or parietal pleura, etc.)was associated with KRAS Q61, OR = 2.177 (95% CI = [0.557, 7.933]); RR2 = 1.656 (95% CI = [1.295, 2.015]); and EGFR mutation RR2 = 1.678 (95% CI = [1.563, 1.791]). Here, KRAS is linked to neoplasm.