A recent study on a Moroccan colon cancer patients cohort showed that KRAS-mutated colon cancers were significantly associated with the female gender, vascular invasion, classical adenocarcinoma phenotype, moderately differentiated tumors, advanced TNM stage (III–IV), left colon tumor localization, and a higher incidence of distant metastases at the time of diagnostic [41]. This evidence concerns the gene KRAS and colonic neoplasm.