Furthermore, LOH 1p/19q is a characteristic signature of oligodendroglioma that generally does not differ markedly in metabolism from IDHmut, non-co-deleted astrocytoma, except for elevated cystathionine levels that may be helpful in distinguishing IDH mutated gliomas with and without LOH 1p/19q [23]. The gene discussed is IDH2; the disease is astrocytoma (excluding glioblastoma).