In addition, immortalized tumor cell lines [7] were reported to express Fscn1 and have frequently been used to as cell models to delineate the interaction of Fscn1 with other cytoskeletal proteins, such as cofilin-1 [8,9] and Daam1 (disheveled-associated activator of morphogenesis 1) [10,11], among others [12]. Here, FSCN1 is linked to neoplasm.