In addition, we found that the culture supernatants derived from inflamed tissues potentiated the invasive and migratory behavior in vitro of autologous primary prostate cells or PCa cell lines, which was inhibited by silencing STAT3 and IL-6 signaling using fludarabine, a STAT3 inhibitor, and tocilizumab, an IL-6 inhibitor. This evidence concerns the gene IL6 and posterior cortical atrophy.