The risk of liver cancer in T2DM insulin users was higher than in the general population (IRR = 5.06, 95% CI 3.24, 7.90); the excess risk was similar when comparing those using insulin alone with those treated with diet alone (IRR = 4.52, 95% CI 1.89, 10.82) (Table 3). Here, INS is linked to type 2 diabetes mellitus.