INS and type 2 diabetes mellitus: The risk was higher among T2DM insulin users than in the general population (IRR = 2.4, 95% CI 1.5, 3.9); the excess risk was similar when comparing those taking insulin alone to patients with T2DM treated with diet alone (IRR = 2.32, 95% CI 0.85, 6.29) (Table 3).