TP53 and cancer: We observed changes in the regulation of multiple processes: upregulation of “p53 signalling pathway (hsa04115)” and “MAPK (mitogen-activated protein kinase) signalling pathway (hsa04010)”; and downregulation of “MicroRNAs in cancer (hsa05206)”; “ECM-receptor interaction (hsa04512)”; “Focal adhesion (hsa04510)”; and “PI3K-Akt signalling pathway (hsa04151)”.