Interestingly, the Mdm2 transcript being a described target of HuR [43,44], and considering the significantly positive correlation between Mdm2 and HuR expression in clinical HCC and human hepatoma cell lines [187], it would be highly expected that the mRNA levels of this E3 ligase were stabilized by HuR during HCC too, despite not having been verified to date. The gene discussed is MDM2; the disease is hepatocellular carcinoma.