Increased KIF11 expression has been reported in a variety of tumors, such as HCC, GBM, CRC, and gallbladder cancer (GBC), and affects the regulation of various signaling pathways, including ERBB2/PI3K/AKT and p53/GSK3β [45,46,47,48]. The gene discussed is ERBB2; the disease is hepatocellular carcinoma.