Of these, 23 markers (BAD, BAX, CDH1, CDK6, CDKN1A, CDKN1B, CTNNB1, EGF, EGFR, FN1, HRAS, IRS2, KRAS, MAPK3, MDM2, MMP2, PDGFC, PIK3CA, PIK3R3, SMAD4, TGFB1, TGFBR2, TLR2) have been covered in the literature very widely, and multiple publications link these, largely through mutations, to many different cancers, including CRC. This evidence concerns the gene TLR2 and colorectal carcinoma.