Interestingly, one of the 42 markers tested (CDKN1A, which encodes p21-a cyclin-dependent kinase inhibitor-1A protein) that has been suggested in the past to have a prognostic value for CRC [63,70,71,72,73] did not show significant changes in the level of mRNA in either of the three tumor tissues tested by qPCR. The gene discussed is CDKN1A; the disease is colorectal carcinoma.