Initial staging (p < 0.001), number of metastatic sites (p < 0.001), liver metastases (p = 0.007), brain metastases (p = 0.037), bone metastases (p = 0.014), hyponatremia (p = 0.037), albumin level (p = 0.046), AP (p = 0.049), type of first-line treatment (p < 0.001) and response to initial chemotherapy (p < 0.001) were significantly associated with long-term survival. The gene discussed is ALB; the disease is Hyponatremia.