The analysis of the tumoral marker in stages III and IV, with (on the left; T4N1, T4N3b) and without (on the right; IVa; T4N0) lymph nodes metastases, confirmed that LSCC cancer showed the maximal ABCG2 expression detectable by WB at stage III and further increased at stage IVa just before metastatization, being downregulated in the more advanced stages (IVb) as compared with previous tumoral stages. This evidence concerns the gene ABCG2 and cancer.