NGFR and cancer: Since we found that p75NTR FL is mainly cytosolic (Figure 7a, lower picture), while p75ICD nuclear localization is prevalent in epithelial cells prior to dysplastic progression (Figure 7b), it is likely that the use of specific p75NTR antibodies is crucial to determine the single specific contribution of p75NTR and p75NTR fragments in cancer tissues and their metastatic progression.