Additionally, we studied the p75NTR level and distribution in adjacent sections and found that p75NTR expression increased in aberrant (Figure 6, Zone 2) as compared with normal (Figure 6, Zone 1) epithelia, and it was still high in stromal LSCC cells of invasive carcinoma (Figure 6, Zone 4), while it underwent an apparent reduction in the front of invasion (Figure 6, Zone 3). This evidence concerns the gene NGFR and invasive carcinoma.