RNF125 and neoplasm: We examined the insertion pattern of transposons in the RNF125 gene in two datasets (Liver-Onc2/HBsAg CISs and Liver-Onc2 CISs) and found that the insertions were scattered throughout the gene and in both transcriptional orientations (Figure 1C), suggesting that RNF125 is likely a tumor suppressor.