Furthermore, we found that CBX8 level in colon cancer was positively correlated with a couple of pluripotentcy-associated genes including BMI1, OCT4, MYC, USP36, RPTOR, UBE2O, JMJD6, SLCO4A1, UTP18, E2F6 and CD44. Here, E2F6 is linked to colonic neoplasm.