RUNX1 and thyroid tumor: A translocation involving CBFA2/RUNX1 Partner Transcriptional Co-Repressor 3 (CBFA2T3, also referred to as ETO2) and GLIS2 has been implicated in acute mega-karyoblastic leukemia, while GLIS1-Paired Box 8 (PAX8) and GLIS3-PAX8 translocations are associated with hyalinizing trabecular tumors, a rare thyroid neoplasm stemming from thyroid follicular cells [13,16,33,35,36,37,38].