TGFB1 and obesity due to melanocortin 4 receptor deficiency: Regarding the obesity group, they found a higher abundance of proteins involved in vesicular transport, catalytic, and chaperon activity in a subcutaneous depot compared to visceral AT whose enrichment is related to immunometabolic processes of obesity, such as TGFB1, CAVN1, monocyte differentiation antigen CD14, mimecan among others, all in comparison to the control group [76].