ATM and obesity due to melanocortin 4 receptor deficiency: Hence, in a murine model of obesity where the animals were fed a high-fat diet, Zhang et al. [52] found a higher expression of miRNA-155 in microvesicles derived from the adipocyte and ATM; additionally, using in-silico analysis authors found SOCS1 to be one of miRNA155 target, thus activating STAT1 while simultaneously inhibiting STAT6.