In addition, Gal (1–29) receptors are widely distributed in the brain [115], including some regions having a special involvement in MDD, such as the dorsal raphe [116,117], where the coexistence of Gal (1–29) and 5-HT was demonstrated by Melander et al. in 1986 [118]. The gene discussed is LGALS1; the disease is major depressive disorder.