However, they also contribute to autoimmune responses in SjS, through triggering the secretion of pro-inflammatory cytokines and chemokines, such as CXCL10 and BAFF, class switch of immunoglobulins and cellular cytotoxicity of NK and T cells [90,144,145,146]. The gene discussed is CXCL10; the disease is Schwartz-Jampel syndrome.