In fact, the ovarian cancer cell line OVCAR-3 with monoallelic losses of BECN1 and LC3 is more sensitive to various autophagy-stressing drugs than the SKOV-3 ovarian cancer cell line without these deletions, while the latter is sensitized by the RNAi knockdown of either BECN1 or LC3 [21]. The gene discussed is MAP1LC3A; the disease is ovarian cancer.