Whereas sepsis patients also showed a decrease in a few pro-inflammatory cytokines i.e., IL-1β, IL-2, IL-12p40, IL-17A, IL-27, TNF-α, and MCP-1; few anti-inflammatory cytokines i.e., IL-1RA, IL-4, IL-27, and TGF-β1; and growth factors, i.e., ENA78, Angiopoietin, TREM1, EOTAXIN, GM-CSF, HGF, PSELECTIN, MMP1, MMP8, MMP12, and MMP13. The gene discussed is IL27; the disease is Sepsis.