In sepsis patients, MELD and MELD Na scores were increased and we observed that neutrophil related proteins i.e., DNAJC13, GPI, GSTP1, PNP, ANPEP, COTL1, PGAM1, APOA1, PROS1, SERPINA3, MPO, and MMRN1 were positively correlated with neutrophils, oxidative burst activity of neutrophils, MELD, MELD Na and bilirubin. Here, SERPINA3 is linked to Sepsis.