It was observed that upregulated proteins in sepsis patients compared to HC were DNAJC13, GPI, GSTP1, PNP, ANPEP, COTL1, GCA, PGAM1, and TMSB4X and compared to w/o sepsis patients were GPI, DNAJC13, and APOA1 (Neutrophil degranulation, neutrophil activation, neutrophil-mediated immunity, and secretory granule lumen (GO:0043312, GO:0002283, GO:0002446, and GO:0034774)) (Figure 5D). The gene discussed is PNP; the disease is Sepsis.