Apart from a few cytokines which were significantly increased in sepsis patients, many were significantly decreased, including IL-1RA, IL-1β, IL-2, IL-4, IL-12p40, IL-17A, IL-27, TNF-α, TGF- β1, MCP-1, ENA78, Angiopoietin, TREM1, EOTAXIN, GM-CSF, HGF, PSELECTIN, MMP1, MMP8, MMP12, and MMP13 in sepsis and w/o sepsis patients compared to HC (Figure 5F). The gene discussed is IL1B; the disease is Sepsis.