CHD2 and fragile X syndrome: The authors went on to ask whether there are human-specific FMRP targets in the FXS forebrain organoids and were able to identify a large number of human-specific FMRP targets via eCLIP-seq, one of which is chromodomain helicase DNA-binding protein 2 (CHD2), a well-known risk gene associated with epilepsy, autism spectrum disorder (ASD), and intellectual disability (Figure 2) [136,137].