LEPR and fatty liver disease: Figure 4K, L shows serum ALT and AST activities, which are biochemical indicators of hepatic damage. The Lepr−/− rats exhibited remarkably higher ALT and AST levels in comparison with the WT rats, as would be expected. However, compared to the Lepr−/− control group, consuming LWE reduced the activities of ALT and AST in Lepr−/− rats by 55.42% and 41.68% (p < 0.05), respectively. These results demonstrated that consuming LWE remarkably alleviated fatty liver and protected hepatic injury in Lepr−/− rats.