Among the EOC tissues examined, CXCR4 expression correlated strongly with expression of proteins related to the epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC), including vimentin, N-cadherin, E-cadherin, CD44, CD133, and NANOG (Figure 1A and Supplementary Figure 1). This evidence concerns the gene CXCR4 and cancer.