EPHA7 and uterine cervix carcinoma in situ: QMSP were performed on a total of 114 TCT specimens. The results showed that the methylation level increased with the progression of cervical disease (P < 0.05), the positive detection rates of methylation were 0% (0/28) in normal tissues, 4.16% (1/24) in CINII, and 11.11% (5/45) in CINIII, and 58.82% (10/17) in cancer (Fig. 5b), and the methylation level of EphA7 increased with the severity of cervical lesions (H = 27.311, P < 0.001).